Mann began her career in 2003, after signing a three-race contract with Manor Motorsport to race in the winter series of the British Formula Renault Championship.
In 2004, she signed with Team JVA and completed a full season. She also competed a European Formula Renault event in Zolder.
In 2005, she signed a two-year contract to drive for Comtec Racing in the Formula Renault Eurocup as well as racing in that year's French Formula Renault 2.0 series. Pippa partnered Westley Barber for the UK based team and learnt a lot during the year.
In 2006 she raced in the UK Formula Renault 2.0 Championship as well as the Eurocup again for race team Comtec Racing, continuing the partnership with John Barnett and Murdoch Cockburn.
In January 2007, Mann signed for Cram by P1 Europe to become the first female to race in the Formula Renault 3.5 Series. In her debut year she managed to score a point and also start from pole position. She competed in the Formula Renault 3.5 Series in 2008 as well, still driving for P1 Motorsport team.
Mann signed to drive for Panther Racing in the 2009 Indy Lights series, the development series for the IndyCar Series.
During her debut season with Panther Racing, Mann scored a string of top-15 finishes, including three top-ten results. However a decision to close the Panther Racing Indy Lights team left her without a 2010 drive.
In December 2009, after deciding to remain in Indianapolis and find a place in another team, Mann confirmed that she would be joining Sam Schmidt Motorsports for the 2010 Indy Lights series. In 2010 she became the first female pole sitter for a race at the Indianapolis Motor Speedway by heading the grid for the Indy Lights Freedom 100, and won her first race at Kentucky Speedway.
On 1 March 2011, Mann tested for the Indianapolis-based IndyCar Series team Conquest Racing at Texas Motor Speedway, and on 19 April, she announced that she would be piloting the No. 36 entry for Conquest Racing in the 2011 Indianapolis 500. On Sunday, 22 May, (Bump Day) Mann qualified 32nd for the 2011 Indianapolis 500, becoming the first British woman ever to qualify for the 500-mile race. During the race, she moved up 12 positions to finish in 20th place, despite a mechanical problem with her on-board water supply that left her severely dehydrated by the end of the race. She was sponsored in the race by Armando Montelongo, former star of the television show Flip This House.
On 13 August 2011, during the final day of practice for the MoveThatBlock.com Indy 225 at New Hampshire Motor Speedway, Mann crashed and suffered an end-plate fracture of the C7 vertebra, but competed on 2 October in the Kentucky Indy 300.
On 16 October 2011, Mann was involved in a 15 car chain reaction crash at Las Vegas Motor Speedway. Mann sustained severe burns to her right little finger and was transported by ground ambulance to a Las Vegas area hospital, where she was admitted for treatment and released the next day, pending later surgery. The crash claimed the life of two-time winner of the Indianapolis 500 Dan Wheldon, and also sent J. R. Hildebrand to hospital with a bruised sternum.
In 2012, Mann was close to attempt qualifying at the Indianapolis 500 for Dale Coyne Racing. The team signed her as third driver for the 2013 edition.
In 2013, Mann finished 30th (out of 33) in the 97th annual Indianapolis 500, completing 46 of 200 laps. She also signed on to make 3 more large oval race starts with Dale Coyne Racing.
In 2014, Mann qualified in 22nd position for the 98th Indianapolis 500 as the only female driver in the field and finished 24th (again out of 33) for Dale Coyne Racing and in partnership with Susan G. Komen. The partnership allowed race fans to donate for each lap Mann completed during the month of May, in support of ending breast cancer. Although encountering an issue during one of the early pit stops, she completed 484 total laps for the month and finished the entire race.
In 2015, Mann returned to the Dale Coyne Racing Team for the 99th Indianapolis 500. She qualified 25th for her 4th appearance with a 4 lap average speed of 223.104 mph, starting from the inside of row 9. Mann finished in 22nd place, racing for the Susan G. Komen cancer outreach organization again for the second year in a row.
After having a successful race at Indy and raising over 50,000 dollars for cancer, Mann was then asked to race again for the Dale Coyne Racing Team recalling her for the June 6th Firestone 600. Starting from the 22nd position, she took 17th place at the Texas Motor Speedway. The Dale Coyne Racing team continued changing drivers on a race-by-race basis throughout the season, with their #18 car recalling Mann for the remaining oval tracks. She started 22nd and finished 13th on the lead lap at the 2015 MAVTV 500 at the Auto Club Speedway. It was the best finish for the #18 car mid way through the season for the team and one of Mann’s best results in her career, since re-joining IndyCar in 2013.
Mann also commentates for IndyCar Radio on the IndyCar Series and Indy Lights series.
You can read more about Pippa's racing career from Wikipedia: